Vijay Gokhale Selected Research

9-(dimethylaminoethoxy)ellipticine

12/2019	In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells.
11/2011	Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex.

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Vijay Gokhale Research Topics

Disease

12	Neoplasms (Cancer) 05/2020 - 11/2005
4	Pain (Aches) 11/2021 - 01/2018
3	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2020 - 11/2012
3	Chronic Pain 01/2019 - 01/2018
3	Carcinogenesis 10/2016 - 10/2012
3	Inflammation (Inflammations) 01/2015 - 06/2010
2	Burkitt Lymphoma (Burkitt's Lymphoma) 12/2019 - 11/2011
2	Neuralgia (Stump Neuralgia) 10/2018 - 01/2018
2	Hypersensitivity (Allergy) 01/2018 - 07/2004
2	Acute Lung Injury 01/2017 - 01/2015
2	Lung Neoplasms (Lung Cancer) 04/2016 - 10/2012
2	Adenocarcinoma 01/2013 - 05/2012
1	Prostatic Neoplasms (Prostate Cancer) 05/2020
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2019
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2019
1	Hyperalgesia 01/2019
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2019
1	Postoperative Pain 01/2018
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 10/2017
1	B-Cell Lymphoma (Lymphoma, B Cell) 10/2017
1	Pneumonia (Pneumonitis) 01/2017
1	Neuroblastoma 04/2016
1	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 04/2016
1	Melanoma (Melanoma, Malignant) 01/2015
1	Asthma (Bronchial Asthma) 01/2015
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 11/2011
1	Colorectal Neoplasms (Colorectal Cancer) 06/2010
1	Multiple Myeloma 11/2008
1	Necrosis 10/2007

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 01/2019 - 11/2005
5	Pharmaceutical PreparationsIBA 11/2021 - 11/2011
4	DNA (Deoxyribonucleic Acid)IBA 10/2017 - 11/2008
4	Biological ProductsIBA 01/2013 - 11/2008
4	Prostaglandins EIBA 01/2013 - 06/2010
2	9-(dimethylaminoethoxy)ellipticineIBA 12/2019 - 11/2011
2	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2019 - 10/2016
2	CalciumIBA 01/2019 - 01/2018
2	Voltage-Gated Sodium ChannelsIBA 10/2018 - 01/2018
2	Peptides (Polypeptides)IBA 01/2018 - 01/2018
2	EnzymesIBA 01/2018 - 10/2012
2	Phosphotransferases (Kinase)IBA 04/2016 - 01/2010
2	ProstaglandinsIBA 10/2012 - 06/2010
1	SodiumIBA 11/2021
1	DNA-Binding Proteins (DNA Binding Protein)IBA 11/2020
1	Androgen Receptors (Androgen Receptor)IBA 05/2020
1	AndrogensIBA 05/2020
1	navitoclaxIBA 12/2019
1	QuinazolinesIBA 01/2019
1	RNA (Ribonucleic Acid)IBA 01/2019
1	LigandsIBA 10/2018
1	Semaphorin-3AIBA 10/2018
1	UbiquitinIBA 10/2018
1	Ion Channels (Ion Channel)IBA 01/2018
1	Amino Acids FDA Link 01/2018
1	Glycoproteins (Glycoprotein)IBA 01/2018
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 10/2017
1	EndotoxinsIBA 01/2017
1	Anaplastic Lymphoma KinaseIBA 04/2016
1	Tyrosine Kinase InhibitorsIBA 04/2016
1	aurinIBA 01/2015
1	quinone methideIBA 01/2015
1	CaspasesIBA 01/2015
1	Small Interfering RNA (siRNA)IBA 01/2015
1	Multifunctional EnzymesIBA 01/2015
1	Myosin-Light-Chain KinaseIBA 01/2015
1	Protein Isoforms (Isoforms)IBA 01/2015
1	CytokinesIBA 10/2012
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 06/2010
1	LipidsIBA 06/2010
1	Phospholipases A2 (Phospholipase A2)IBA 06/2010
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2010
1	Protein Kinases (Protein Kinase)IBA 01/2010
1	psorosperminIBA 11/2008
1	Alkylating AgentsIBA 11/2008
1	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2008
1	Type II DNA Topoisomerases (Topoisomerase II)IBA 11/2008
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2008
1	Acetylcysteine (Siran)FDA LinkGeneric 10/2007
1	hydroquinone (Esoterica)FDA Link 10/2007
1	ThioredoxinsIBA 04/2007
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 11/2005
1	Biomarkers (Surrogate Marker)IBA 11/2005
1	ElementsIBA 07/2004

Therapy/Procedure

3	Therapeutics 11/2021 - 01/2019
2	Drug Therapy (Chemotherapy) 01/2019 - 11/2008
1	Castration 05/2020
1	Ligation 01/2019
1	Chemoprevention 06/2010